Advisor Shubhik K DebBurman Department of Biology Biology Diagrams Abstract. Budding yeast, Saccharomyces cerevisiae, is widely used as a model organism to study the genetics underlying eukaryotic cellular processes and growth critical to cancer development, such as cell division and cell cycle progression.The budding yeast cell cycle is also one of the best-studied dynamical systems owing to its thoroughly resolved genetics. Budding yeast, Saccharomyces cerevisiae, is a model organism for studying regulation of the eukaryotic cell cycle.The complex gene-protein interaction network controlling the yeast cell division
Our model provides a good match with experimental observations of many important characteristics of the budding yeast cell cycle, including inter-division time, cell size, and the phenotypes of
A stochastic model of size control in the budding yeast cell cycle Biology Diagrams
Bifurcation analysis of a model for the budding yeast cell cycle has identified only two different steady states (one for G1 and one for mitosis) using cell mass as a bifurcation parameter. By analyzing the same model, using different methods of dynamical systems theory, we provide evidence for transitions among several different steady states
The budding yeast Saccharomyces cerevisiae has long been a leading model organism for cell cycle studies. The numerous advantages to working with S. cerevisiae include the fact that it is easily grown in the lab, has a comparatively short generation time (typically 90 minutes for a wild type strain at 30 ยฐC) and has less susceptibility to
PDF Visualization of the Budding Yeast Cell Cycle Biology Diagrams
Model description. The model we explore in this paper is based on the molecular regulatory network originally proposed by Chen et al. [].Chen's model is a comprehensive deterministic model that accounts for average properties of wild-type budding yeast cells, in addition to the phenotypes of more than 100 mutant strains.
